Based on the acclaimed video game The Last of Us, the story takes place 20 years after modern civilization has been destroyed. Joel (Pascal), a hardened survivor, is hired to smuggle Ellie (Ramsey), a 14-year-old girl, out of an oppressive quarantine zone. What starts as a small job soon becomes a brutal, heartbreaking journey, as they both must traverse across the U.S. and depend on each other for survival.
Pierce will recur as Perry, a rebel in a quarantine zone. Bartlett guest stars as Frank and O’Neill is Bill, two post-pandemic survivalists living alone in their own isolated town.